Rama Natarajan Selected Research

Angiotensin II

5/2023	Genetic Deletion of the LINC00520 Homolog in Mouse Aggravates Angiotensin II-Induced Hypertension.
12/2018	A Novel Angiotensin II-Induced Long Noncoding RNA Giver Regulates Oxidative Stress, Inflammation, and Proliferation in Vascular Smooth Muscle Cells.
11/2017	Regulation of angiotensin II actions by enhancers and super-enhancers in vascular smooth muscle cells.
5/2014	Noncoding RNAs in vascular disease.
7/2013	Novel long noncoding RNAs are regulated by angiotensin II in vascular smooth muscle cells.
5/2012	Small RNA sequencing reveals microRNAs that modulate angiotensin II effects in vascular smooth muscle cells.
3/2008	Products of 12/15-lipoxygenase upregulate the angiotensin II receptor.
5/2005	Angiotensin II enhances interleukin-18 mediated inflammatory gene expression in vascular smooth muscle cells: a novel cross-talk in the pathogenesis of atherosclerosis.
3/2002	The oxidized lipid and lipoxygenase product 12(S)-hydroxyeicosatetraenoic acid induces hypertrophy and fibronectin transcription in vascular smooth muscle cells via p38 MAPK and cAMP response element-binding protein activation. Mediation of angiotensin II effects.

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Rama Natarajan Research Topics

Disease

32	Diabetic Nephropathies (Diabetic Nephropathy) 11/2023 - 11/2003
20	Diabetes Complications 01/2021 - 05/2003
16	Hypertrophy 01/2018 - 03/2002
16	Atherosclerosis 11/2017 - 06/2003
14	Inflammation (Inflammations) 01/2023 - 04/2003
12	Hypertension (High Blood Pressure) 05/2023 - 04/2003
9	Obesity 01/2023 - 04/2005
8	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 11/2023 - 10/2006
8	Diabetic Angiopathies (Diabetic Angiopathy) 01/2021 - 09/2003
8	Hyperglycemia 11/2020 - 05/2006
8	Proteinuria 01/2016 - 03/2005
7	Fibrosis (Cirrhosis) 01/2022 - 07/2009
6	Diabetes Mellitus 10/2020 - 01/2005
6	Kidney Diseases (Kidney Disease) 01/2016 - 04/2003
5	Neoplasms (Cancer) 01/2023 - 12/2014
5	Albuminuria 05/2016 - 01/2005
4	Insulin Resistance 12/2022 - 04/2005
4	Cardiovascular Diseases (Cardiovascular Disease) 12/2018 - 01/2005
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 08/2013 - 07/2004
3	Breast Neoplasms (Breast Cancer) 09/2022 - 01/2020
3	Chronic Renal Insufficiency 08/2015 - 05/2011
3	Vascular Diseases (Vascular Disease) 05/2014 - 10/2005
2	Carcinogenesis 11/2022 - 12/2021
2	Hypoxia (Hypoxemia) 08/2022 - 01/2020
2	Type 2 Diabetes Mellitus (MODY) 11/2020 - 10/2007
2	Dyslipidemias (Dyslipidemia) 03/2016 - 09/2013
2	Polycystic Kidney Diseases (Polycystic Kidney Disease) 01/2016 - 05/2011
2	Disease Progression 07/2015 - 05/2007
1	Hyperinsulinism (Hyperinsulinemia) 12/2022
1	Triple Negative Breast Neoplasms 08/2022
1	Glucose Intolerance 01/2022
1	Weight Gain 01/2022
1	Autoimmune Diseases (Autoimmune Disease) 01/2021

Drug/Important Bio-Agent (IBA)

25	MicroRNAs (MicroRNA)IBA 01/2023 - 07/2009
12	Histones (Histone)IBA 01/2022 - 05/2007
12	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2021 - 04/2003
12	Arachidonate 15-Lipoxygenase (Arachidonate 15 Lipoxygenase)IBA 03/2016 - 06/2003
11	Biomarkers (Surrogate Marker)IBA 11/2023 - 05/2011
11	ChromatinIBA 01/2022 - 05/2007
11	CytokinesIBA 01/2021 - 05/2003
9	Angiotensin IIIBA 05/2023 - 03/2002
9	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 12/2003
9	Proteins (Proteins, Gene)FDA Link 05/2016 - 03/2002
8	Long Noncoding RNAIBA 01/2023 - 12/2014
8	Advanced Glycation End ProductsIBA 09/2013 - 09/2003
7	Oxidants (Oxidizing Agents)IBA 03/2016 - 04/2003
6	ChemokinesIBA 11/2022 - 05/2003
6	LipidsIBA 03/2016 - 03/2002
6	EnzymesIBA 01/2016 - 11/2003
6	Streptozocin (Streptozotocin)FDA Link 01/2016 - 03/2005
5	AcidsIBA 03/2016 - 03/2002
5	CollagenIBA 12/2014 - 12/2003
5	Lysine (L-Lysine)FDA Link 02/2014 - 05/2007
4	Extracellular Matrix ProteinsIBA 09/2015 - 12/2006
3	Insulin (Novolin)FDA Link 12/2022 - 12/2014
3	Interleukin-6 (Interleukin 6)IBA 12/2018 - 05/2006
3	Hydroxyeicosatetraenoic Acids (HETE)IBA 03/2016 - 04/2003
3	LigandsIBA 12/2014 - 05/2006
3	Fibronectins (Fibronectin)IBA 03/2012 - 03/2002
3	Transforming Growth Factor beta (TGF-beta)IBA 07/2009 - 12/2008
3	NF-kappa B (NF-kB)IBA 12/2008 - 07/2006
3	p38 Mitogen-Activated Protein KinasesIBA 12/2008 - 03/2002
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2008 - 05/2006
3	Arachidonate 12-Lipoxygenase (12 Lipoxygenase)IBA 01/2005 - 03/2002
3	Lipoxygenase (Lipoxygenase-1)IBA 11/2003 - 03/2002
2	Nonesterified Fatty Acids (NEFA)IBA 01/2023 - 01/2021
2	Androgen Receptors (Androgen Receptor)IBA 09/2022 - 08/2022
2	oxidized low density lipoproteinIBA 01/2020 - 01/2012
2	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 05/2016
2	OligonucleotidesIBA 09/2016 - 10/2007
2	Transcription Factors (Transcription Factor)IBA 01/2016 - 06/2003
2	alpha2 Subunit Collagen Type IIBA 12/2014 - 10/2010
2	Receptor for Advanced Glycation End ProductsIBA 12/2014 - 05/2006
2	Losartan (Cozaar)FDA LinkGeneric 02/2014 - 04/2005
2	Transforming Growth Factors (Transforming Growth Factor)IBA 09/2013 - 05/2012
2	Phosphotransferases (Kinase)IBA 08/2013 - 07/2009
2	CreatinineIBA 05/2011 - 10/2007
2	Quinapril (Accupril)FDA LinkGeneric 01/2007 - 07/2004
2	Interferon-gamma (Interferon, gamma)IBA 10/2006 - 05/2006
2	Interleukin-18 (Interleukin 18)IBA 05/2006 - 05/2005
2	Arachidonic Acid (Vitamin F)IBA 04/2003 - 03/2002
1	Pyruvaldehyde (Methylglyoxal)IBA 11/2023
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2023
1	Single-Stranded DNA (DNA, Single Stranded)IBA 01/2023
1	Palmitic Acid (Hexadecanoic Acid)IBA 01/2023
1	Transcription Factor CHOPIBA 12/2022
1	Antigen Receptors (Antigen Receptor)IBA 11/2022
1	Oxygen (Dioxygen)IBA 08/2022
1	AndrogensIBA 08/2022
1	Metformin (Glucophage)FDA LinkGeneric 01/2022
1	KinesinsIBA 12/2021
1	AutoantigensIBA 01/2021
1	FatsIBA 01/2020
1	LDL Lipoproteins (beta Lipoproteins)IBA 01/2020
1	Environmental CarcinogensIBA 01/2020
1	SugarsIBA 01/2020
1	Endocrine DisruptorsIBA 01/2020

Therapy/Procedure

15	Therapeutics 12/2022 - 01/2007
8	Glycemic Control 11/2020 - 07/2008
1	Drug Therapy (Chemotherapy) 01/2023